I club the MDX because the lack of a touchscreen is virtually a deal killer (and may ultimately prove to be an actual deal killer for me). But there are also other things. Almost every other vehicle in its class has electronic controls of some kind for the third row. Almost every other vehicle has a three pronged outlet (ground hole) while the MDX does not. Most other manufacturers have some sort of automatic parking. The GV80 has remote parking where you can actually move the vehicle forward and backward while outside your vehicle.
The GV80 has electronic third row seats, ventilated 2nd row, a spot to store the cargo cover, a touchscreen, and the aforementioned parking assist. And after seeing a 73K MSRP GV80 in person, I didn't feel the Type S was particularly superior. It was a close call with the Type S Advance having superior suspension.
Just some counterpoints for sake of discussion -
Touchscreen - already discussed at length but as one who doesn't have a 4th gen MDX but would strongly consider one given the great experience I've had with my 3rd gen, this certainly wouldn't be a big deal to me even though I agree it'd be better if Acura provided both input options and then let the user decide which one they want to use.
Third row - I'm not sure what you mean by 'electronic controls' for it but if you mean power folding/lifting of the seat, I can see some utility but also see more potential things to break and the utility will depend on the usage. I actually rarely use the seat so putting it up/down by hand when I want to use it isn't that big of a deal.
Outlet - A 12v DC to AC inverter for a car is about $30. I actually bought one some years ago for 'just in case' and have kept it in the car but have never used it. I don't see a strong need for one unless one needs to plug in a laptop because the 3-5 hours on battery isn't adequate for them but in that niche case most laptop adapters are 2 prong so if there's a 2 prong outlet available it's adequate. For even more niche cases they can always spend the $30 for an inverter like I did.
Auto parking - Maybe it's a case of 'you don't know what you're missing' since I've never had such a thing but I was actually thinking about this type of feature recently and see no point to it for me. If a spot is so tight that I'd have some difficulty parallel parking it myself then I don't want to park my vehicle in that spot since chances are very good the cars on either end of it will hit it when they pull out. I can manage to parallel park in a reasonable spot just fine.
Again, to me these are all just little nits of features that pale in comparison to how the vehicle actually drives and handles and seat comfort, which are attributes far more important to me than the gimmicks. I also consider the point of how often or long I'd actually use one of the features/gimmicks because it translates to what real value it has - i.e. when driving I just don't need to mess with the screen that much so no big deal, I rarely put the 3rd row seat up/down so no big deal, I wouldn't park in a tight spot due to potential damage from other cars so no big deal on self parking, etc.
Driving 100+ mph and acceleration to get to it - also no big deal to me because in the USA I don't ever drive 100mph and don't even drive 90mph. I do drive 85mph where permitted (Utah, I think maybe some of Texas, etc.). I haven't driven the 4th gen but the 3rd gen gets up to 90mph plenty quickly enough. If I were to drive an MDX in Germany, i.e. if I brought one over there with me, then driving 100+ mph would be important because I've driven those speed a lot over there where it's safe to do so. But I have no plans to move to Germany and bring an MDX there with me.