it might be wise to wait a couple months after launch instead of buying the first vehicles off the production line as there are likely to be some production inconsistencies when they first stand up the line and start building a brand new model for the very first time.
It might be but realistically car manufacturers aren't that quick to react to many of the issues and indeed many issues don't really come to light until many months after the sale when enough feedback has been aggregated by the manufacturer to start to do something about it and the fix itself could be a very long process since they sometimes need to work with their suppliers of the component, perhaps go through a redesign, and then start to incorporate the change into the line. In addition, a warranty goes a long way towards ameliorating the issues.
On top of that, there's the issue of when exactly is the 'first year' to avoid? For example, I bought a 2014 MDX that had a carryover transmission in it and a somewhat carryover engine in it. People who waited a couple of years into the 3rd gen found themselves with a completely different and brand new trans in the vehicle and one that wasn't trouble free for all. Yet later models introduced the hybrid which now had a different engine, yet a different trans, and the complexities of the hybrid aspect.
Moreover, on the intro model, including the very first ones to roll off the line, most of the issues could have been readily detected by one who would have done a thorough inspection of the vehicles along with a reasonable test drive and spending some seat time in the vehicle even on the showroom floor because in doing that they would have detected any panel alignment issues, rear thumps, noisy fuel pump, an infotainment system perhaps not to their liking (but perhaps not intermittent glitches), etc. - i.e. all of the items that seemed to be the more frequently complained about issues by those who happened to experience them.
Given that, I don't really discount what you're saying and if it was no impact one way or the other I also would likely prefer to not get the first ones that roll off on a new model although that definition really needs to be not the 'generation' of the vehicle but the generation and also the major components of engine, trans, suspension, etc. since a change in any of the latter is essentially like a new model. But if I was ready to buy, as I was when I got the 2014 (since my existing SUV had 200K miles on it) I wouldn't hesitate to get one with the condition that I'd do a thorough inspection and would take advantage of the warranty for anything that's wrong.